Publication date: 01-11-2019

Special Issue Agronomy: Domestication and Transcription Factors

The journal Agronomy (ISSN 2073-4395, IF 2.259) is currently running a Special Issue entitled "Domestication and Transcription Factors Related to Important Traits in Horticultural Crops". Dr. Raquel Sánchez-Pérez is serving as Guest Editor for this issue. Based on your expertise in this field, we think you could make an excellent contribution.


As part of evolution, domestication has enabled wild plants and animals to be cultivated and consumed. This domestication occurred spontaneously or by humans, to adapt to a new environment. As a result, plants have developed new traits, such as bigger branches, bigger and sweeter fruits, etc., in which many transcription factors have a major role. When, where, and how most horticultural crops are domesticated today is being elucidated by the combination of different disciplines: archaeobotany, breeding, biochemistry, bioinformatics, physiology, molecular biology, etc. [...]


For further reading, please follow the link to the Special Issue Website at:


The submission deadline is 31 August 2020. You may send your manuscript now or up until the deadline. Submitted papers should not be under consideration for publication elsewhere. We also encourage authors to send a short abstract or tentative title to the Editorial Office in advance (


Agronomy is fully open access. Open access (unlimited and free access by readers) increases publicity and promotes more frequent citations, as indicated by several studies. Open access is supported by the authors and their institutes. An Article Processing Charge (APC) of CHF 1000 currently applies to all accepted papers. You may be entitled to a discount if you have previously received a discount code or if your institute is participating in the MDPI Institutional Open Access Program (IOAP), for more information see:


For further details on the submission process, please see the instructions for authors at the journal website (


We look forward to hearing from you.


Kind regards,


Ms. Leah Lu

Assistant Editor


Mutation of a bHLH transcription factor allowed almond domestication

Publication date: 14-06-2019

Authors: Sánchez-Pérez R*, Pavan S, Mazzeo R, Moldovan C, Aiese R, Del Cueto J, Ricciardi F, Lotti C, Ricciardi L, Dicenta F, López-Marqués R, Møller BL

Journal: Science

Wild almond species accumulate the bitter and toxic cyanogenic diglucoside amygdalin. Almond domestication was enabled by the selection of genotypes harboring sweet kernels. We report the completion of the almond reference genome. Map-based cloning using an F1 population segregating for kernel taste led to the identification of a 46-kilobase gene cluster encoding five basic helix-loop-helix transcription factors, bHLH1 to bHLH5. Functional characterization demonstrated that bHLH2 controls transcription of the P450 monooxygenase–encoding genes PdCYP79D16 and PdCYP71AN24, which are involved in the amygdalin biosynthetic pathway. A nonsynonymous point mutation (Leu to Phe) in the dimerization domain of bHLH2 prevents transcription of the two cytochrome P450 genes, resulting in the sweet kernel trait.



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